KMID : 0605720200260020154
|
|
Journal of the Korean Society of Biological Therapies in Psychiatry 2020 Volume.26 No. 2 p.154 ~ p.161
|
|
A Comparative Study on the Cognitive and Clinical Characteristics of Childhood/Adolescent- and Adult-Onset of Bipolar Disorder
|
|
Kim Hyeon-Mi
Huh Sung-Young Kim Sung-Gon Kim Ji-Hoon Jung Woo-Young Yu Eun-Ra Choi Bum-Sung Kim Dae-Wook Yoon Dong-Uk
|
|
Abstract
|
|
|
Objectives£ºChildhood/adolescent-onset of bipolar disorder presents functional impairments on emotional, academic, and social aspects. These impairments could continue into adulthood. However, there are few studies comparing cognitive function between childhood/adolescent- and adult-onset using psychological test. This study aims to improve understanding of childhood/adolescent-onset of bipolar disorder by comparing differences in cognitive function, clinical and demographic features between the two groups.
Methods£ºThis study was conducted on 145 patients diagnosed with bipolar disorder type I, II, and other specified bipolar disorder by DSM 5 at the time of discharge from 2016 to 2019 at the Department of Psychiatry, Pusan National University Yangsan Hospital. Demographic information, clinical data, and results of psychological tests (K-WISC-IV, K-WAIS-IV) were collected and reviewed.
Results£ºChildhood/adolescent-onset group was significantly low in total potential IQ and in language understanding than adult-onset group (p=0.008 and p=0.013). The childhood/adolescent group had significantly more psychiatric comorbidities than the adult group (p<0.001). The average number of prescribed antipsychotic agents was 1.18 (SD= ¡¾0.64) in the childhood/adolescent group, and 1.78 (SD=¡¾0.82) in the adult group. The difference was statistically significant (p<0.001).
Conclusion£ºPatients with childhood/adolescent-onset bipolar disorder have lower total potential IQ and language understanding comparing patients with adult-onset bipolar disorder. This highlights the importance of conducting a well-designed prospective study to find out more about the characteristics of childhood/adolescent-onset bipolar disorder.
|
|
KEYWORD
|
|
Early onset, Cognitive function, Bipolar disorder
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|